SHANGHAI, April 17, 2023 /PRNewswire/ — Glucose monitoring is a key link in diabetes management. Currently, there are two main methods of self-monitoring of glucose in patients with diabetes, one is traditional blood glucose monitoring (BGM), and the other is continuous glucose monitoring (CGM). ). CGM can provide dynamic, comprehensive and reliable all-day glucose information to understand the trend of glucose fluctuations, and detect hidden hyperglycemia and hypoglycemia, thus becoming a new trend in glucose monitor.
Principles and technical difficulties of CGM
The structure design and installation position of temperature sensor NST1002 used in CGM
CGM allows real-time monitoring of glucose concentration in subcutaneous tissue fluid by implanting glucose sensors. The sensor is the core part of the CGM system with high barriers, which directly determines whether the measurement results of the CGM system are accurate. The sensor electrode, film layer, sensing layer and calibration algorithm are also the key to determine the performance.
The CGM system measures the concentration of glucose in the interstitial fluid. Although there is a high correlation with glucose concentration, the difference between the two is not constant. There are many differences between the concentration difference and the time to reach the equilibrium concentration in different physiological conditions such as rest, after eating, exercise, breathing and hypoxia. In addition, factors such as electrode passivation and exotic reactant coating on the surface of the sensor can also cause the sensitivity of the sensor to change with the change of implantation time. In actual application, environmental temperature, external pressure and other factors may bring measurement errors.
The above problems can be solved by the calibration algorithm. In the calibration algorithm model, as an important variable, the ambient temperature or body surface temperature has an important effect on the effectiveness of the algorithm model.
The NST1002 facilitates accurate CGM measurements
NOVOSENSE NST1002 is a high-precision, low-power temperature sensor that can detect changes in ambient temperature or body surface temperature in real time and adjust the algorithm to make glucose monitoring more accurate.
In the actual use of CGM products, the structure design and installation position of the NST1002 is more convenient. In terms of structural design, NST1002 can be close to the skin of the body surface to achieve accurate collection of body surface temperature, to provide more effective data.
With accumulated rich experience in surface temperature acquisition solutions, NOVOSENSE temperature sensor can help customers to easily complete product structure design and material selection. The flexible probe of the interstitial fluid glucose sensor is less than 0.4 mm in diameter and can be inserted 5 mm under the skin to ensure accurate sensing of the glucose concentration in the interstitial fluid outside the cells.
SOURCE Novosense